2022-23 NFL Week 5: Indianapolis Colts vs. Denver Broncos October 6, 2022 by Marc Jerbs

On Thursday, the Indianapolis Colts will face the Denver Broncos to start Week 5 of the 2022-23 NFL season.

Kick-off is set 8:15PM EDT at the Empower Field in Denver, Colorado.

Colts's QB Matt Ryan has found a transition problem with his new team.

In his first four games, he's amassed eight turnovers, sacked fifteen times and has nine fumbles after leaving Atlanta in the offseason and join the Indianapolis Colts.

However, it is not Matt Ryan's fault alone since Indianapolis is missing key players this season due to injuries.

Broncos' QB Russell Wilson is also playing for a new team after leaving the Seattle Seahawks.

He's also having a difficult time adjusting in Denver but he's confident that they will turn it around.

Denver is also ravaged by injuries to its key players but other players must step up its game while they are away.

The sportsbook handicappers have installed the Denver Broncos as the favorites to win over the Indianapolis Colts on Thursday night.