2021-22 NFL Week 12: Buffalo Bills vs. New Orleans Saints November 25, 2020 by Marc Jerbs

On Thursday, the Buffalo Bills will play the New Orleans Saints in the last game of the triple-header Thanksgiving Day match for the 2021-22 NFL Week 12.

Kick-off is set 8:20PM EST at the Caesar Superdome.

The Buffalo Bills failed to notch its 2nd consecutive match as they fell 41-15 to the Indianapolis Colts in Week 11.

The loss dropped Buffalo into to 2nd place in the AFC East behind New England.

Bills' QB Josh Allen must lead anew his team as they are prime to redeem their humiliating loss in Week 11.

He's sixth in the NFL with 2,811 passing yards, tied for fifth with 21 touchdowns and ninth with a 58.8 QB rating.

The New Orleans Saints have struggled in their last three games and would want to break their three-game losing streak as they fight to stay alive in the NFL playoff picture.

New Orleans' defense will be busy once they face QB Josh Allen and the Bills.

Expect LB Demario Davis, CB Marshon Lattimore and six-time Pro Bowler DE Cameron Jordan to anchor Buffalo's defense.

The sportsbook handicappers have installed the New Orleans Saints as the favorites to win over the Buffalo Bills on Thursday's Thanksgiving Day match.